apalutamide will minimize the level or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medications which might be CYP3A4 substrates can lead to reduce publicity to these remedies.the skin, tongue or lips switch blue, gre